1952359-26-0

1952359-26-0 structure

Name: Corixetan
Chemical Name: 4-{[4-(3-[Bis(2-{[(3-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyridinyl)carbonyl]amino}ethyl)amino]-2-{[bis(2-{[(3-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyridinyl)carbonyl]amino}ethyl)amino]methyl}propyl)phenyl]amino}-4-oxobutanoic acid
CAS Number: 1952359-26-0
Molecular Formula: C₅₀H₆₁N₁₁O₁₅
Molecular Weight: 1056.08
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Cytotoxin
Create Date: 2021-12-20 00:42:38
Modify Date: 2024-01-10 18:45:29
Corixetan is a highly efficient thorium chelator. Corixetan can efficiently complex Th-227 with sufficient in vivo stability[1].

Name	4-{[4-(3-[Bis(2-{[(3-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyridinyl)carbonyl]amino}ethyl)amino]-2-{[bis(2-{[(3-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyridinyl)carbonyl]amino}ethyl)amino]methyl}propyl)phenyl]amino}-4-oxobutanoic acid
Synonyms	Butanoic acid, 4-[[4-[3-[bis[2-[[(1,2-dihydro-3-hydroxy-1-methyl-2-oxo-4-pyridinyl)carbonyl]amino]ethyl]amino]-2-[[bis[2-[[(1,2-dihydro-3-hydroxy-1-methyl-2-oxo-4-pyridinyl)carbonyl]amino]ethyl]amino]methyl]propyl]phenyl]amino]-4-oxo- 4-{[4-(3-[Bis(2-{[(3-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyridinyl)carbonyl]amino}ethyl)amino]-2-{[bis(2-{[(3-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyridinyl)carbonyl]amino}ethyl)amino]methyl}propyl)phenyl]amino}-4-oxobutanoic acid

Description	Corixetan is a highly efficient thorium chelator. Corixetan can efficiently complex Th-227 with sufficient in vivo stability[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin
Target	Traditional Cytotoxic Agents
References	[1]. Ramdahl T, et al. An efficient chelator for complexation of thorium-227. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4318-21.