LSN 3213128
Modify Date: 2025-08-25 18:23:01
LSN 3213128 structure
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Common Name | LSN 3213128 | ||
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| CAS Number | 1941211-99-9 | Molecular Weight | 409.46 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H16FN3O4S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LSN 3213128LSN 3213128 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells. Anti-tumor activity[1]. |
| Name | LSN 3213128 |
|---|
| Description | LSN 3213128 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells. Anti-tumor activity[1]. |
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| Related Catalog | |
| Target |
IC50: 16 nM (AICARFT), 19 nM (AICARFT in cells)[1] |
| References |
| Molecular Formula | C17H16FN3O4S2 |
|---|---|
| Molecular Weight | 409.46 |
| InChIKey | DSUZLJDXUJUTGI-LLVKDONJSA-N |
| SMILES | O=c1[nH]ccc2cc(F)c(NS(=O)(=O)c3ccc(N4CCC(O)C4)s3)cc12 |