Dihydrocapsaicin

Modify Date: 2025-08-20 17:30:05

Dihydrocapsaicin Structure
Dihydrocapsaicin structure
 Common Name Dihydrocapsaicin
CAS Number 19408-84-5 Molecular Weight 307.428
Density 1.0±0.1 g/cm3 Boiling Point 457.3±55.0 °C at 760 mmHg
Molecular Formula C18H29NO3 Melting Point 62-65 °C(lit.)
MSDS Chinese USA Flash Point 230.4±31.5 °C
Symbol GHS06
GHS06		 Signal Word Danger

 Use of Dihydrocapsaicin


Dihydrocapsaicin is a natural capsaicin, acts as a selective TRPV1 agonist, and also increases p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection[1][2].

 Names

Name dihydrocapsaicin
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 457.3±55.0 °C at 760 mmHg
Melting Point 62-65 °C(lit.)
Molecular Formula C18H29NO3
Molecular Weight 307.428
Flash Point 230.4±31.5 °C
Exact Mass 307.214752
PSA 58.56000
LogP 4.72
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.508
Storage condition 2-8°C
Water Solubility H2O: insoluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RA5998000
CHEMICAL NAME :
Nonanamide, 8-methyl-N-vanillyl-
CAS REGISTRY NUMBER :
19408-84-5
BEILSTEIN REFERENCE NO. :
2815150
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C18-H29-N-O3
MOLECULAR WEIGHT :
307.48

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
5 mg/L
REFERENCE :
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 48,109,1989

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H315-H319-H335
Precautionary Statements P261-P301 + P310-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T:Toxic;
Risk Phrases R25;R36/37/38
Safety Phrases S22-S26-S28-S36/39-S45-S36/37/39
RIDADR UN 2811 6.1/PG 2
WGK Germany 3
RTECS RA8530000
Packaging Group II
Hazard Class 6.1(a)
HS Code 3302109090

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles34

More Articles
Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

Inhibition by capsaicin and its related vanilloids of compound action potentials in frog sciatic nerves.

Life Sci. 92(6-7) , 368-78, (2013)

Although capsaicin not only activates transient receptor potential vanilloid-1 (TRPV1) channels but also inhibits nerve conduction, the latter action has not yet been fully examined. The purpose of th...

Optimization and validation of liquid chromatography and headspace-gas chromatography based methods for the quantitative determination of capsaicinoids, salicylic acid, glycol monosalicylate, methyl salicylate, ethyl salicylate, camphor and l-menthol in a topical formulation.

J. Pharm. Biomed. Anal. 60 , 51-8, (2012)

Capsaicinoids, salicylic acid, methyl and ethyl salicylate, glycol monosalicylate, camphor and l-menthol are widely used in topical formulations to relieve local pain. For each separate compound or si...

 Synonyms

N-(4-Hydroxy-3-methoxybenzyl)-8-methylnonanamide
Nonanimidic acid, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-, (1Z)-
(1Z)-N-(4-Hydroxy-3-methoxybenzyl)-8-methylnonanimidic acid
6,7-Dihydrocapsaicin
8-methyl-nonanoic acid vanillylamide
N-[(4-Hydroxy-3-methoxy-phenyl)methyl]-8-methyl-nonanamide
Nonanamide,8-methyl-N-vanillyl
Dihydro Capsaicin
MFCD00017259
N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnonanamide
Nonanamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-
8-Methyl-N-vanillyl-nonamide
Dihydrocapsaicin
Nonanamide, 8-methyl-N-vanillyl-
EINECS 206-969-8
8-Methyl-N-vanillylnonanamide
N-(4-hydroxy-3-methoxybenzyl)isodecanamide
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