5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one

Modify Date: 2025-08-27 16:11:22

5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one structure	Common Name	5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one
	CAS Number	19275-46-8	Molecular Weight	410.460
	Density	1.3±0.1 g/cm3	Boiling Point	615.9±55.0 °C at 760 mmHg
	Molecular Formula	C₂₄H₂₆O₆	Melting Point	155-160ºC
	MSDS	N/A	Flash Point	212.3±25.0 °C

Use of 5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one

3-Isomangostin, extracted from Garciniamangostana.L. shell, is a potent MutT homologue 1 (MTH1) inhibitor with an IC50 value of 52 nM. 3-isomangostin would be an attractive chemical tool for the development of anticancer agents[1].

Name	3-isomangostin
Synonym	More Synonyms

Description	3-Isomangostin, extracted from Garciniamangostana.L. shell, is a potent MutT homologue 1 (MTH1) inhibitor with an IC50 value of 52 nM. 3-isomangostin would be an attractive chemical tool for the development of anticancer agents[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Yokoyama T, et al. Discovery of a new class of MTH1 inhibitor by X-ray crystallographic screening. Eur J Med Chem. 2019 Apr 1;167:153-160.

Density	1.3±0.1 g/cm3
Boiling Point	615.9±55.0 °C at 760 mmHg
Melting Point	155-160ºC
Molecular Formula	C₂₄H₂₆O₆
Molecular Weight	410.460
Flash Point	212.3±25.0 °C
Exact Mass	410.172943
PSA	89.13000
LogP	5.72
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.605

alpha-Mangostin

CAS#:6147-11-1

~50%

5,9-Dihydroxy-8...

CAS#:19275-46-8

1-Isomangostin

CAS#:19275-44-6

13-Hydroxy-2-is...

CAS#:207984-92-7

Literature: Australian Journal of Chemistry, , vol. 51, # 3 p. 249 - 254

alpha-Mangostin

CAS#:6147-11-1

3-Isomangostin ...

CAS#:26063-96-7

5,9-Dihydroxy-8...

CAS#:19275-46-8

3,4-dihydro-5,9...

CAS#:112649-47-5

Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, # 1-12 p. 281 - 282

Precursor 1
CAS#:6147-11-1 alpha-Mangostin
DownStream 0

5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one

5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-but-2-enyl)-3,4-dihydro-2H-pyrano[3,2-b]xanthen-6-one

2H,6H-Pyrano[3,2-b]xanthen-6-one, 3,4-dihydro-5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-

9-hydroxycalabaxanthone

3,4-Dihydro-5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-butenyl)-2H,6H-pyrano[3,2-b]xanthen-6-one

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one

Use of 5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.