PF-06463922 acetate
Modify Date: 2024-09-06 11:51:56
PF-06463922 acetate structure
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Common Name | PF-06463922 acetate | ||
|---|---|---|---|---|
| CAS Number | 1924207-18-0 | Molecular Weight | 466.465 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H23FN6O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF-06463922 acetatePF-06463922 acetate is a potent, selective brain-penetrable inhibitor of both anaplastic lymphoma kinase (ALK) and c-ros Oncogene 1 (ROS1) with strong activity against all known ALK and ROS1 mutants identified in patients with crizotinib-resistant disease. PF-06463922 is in clinical trials for the treatment of non–small cell lung cancer (NSCLC). |
| Name | Lorlatinib acetate |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C23H23FN6O4 |
|---|---|
| Molecular Weight | 466.465 |
| Exact Mass | 466.176483 |
| Lorlatinib acetate |
| (16R)-19-Amino-13-fluoro-4,8,16-trimethyl-9-oxo-17-oxa-4,5,8,20-tetraazatetracyclo[16.3.1.02,6.010,15]docosa-1(22),2,5,10,12,14,18,20-octaene-3-carbonitrile acetate (1:1) |
| (10R).7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H.8,4-(metheno)pyrazolo[4,3.h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile acetate |
| PF-06463922 acetate |
| 2H-8,4-Methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile, 7-amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-, (10R)-, acetate (1:1) |