Benzo[e]pyrene

Modify Date: 2024-01-04 00:34:37

Benzo[e]pyrene structure	Common Name	Benzo[e]pyrene
	CAS Number	192-97-2	Molecular Weight	252.309
	Density	1.3±0.1 g/cm3	Boiling Point	467.5±12.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₁₂	Melting Point	177-180ºC(lit.)
	MSDS	Chinese USA	Flash Point	228.6±13.7 °C
	Symbol	GHS08, GHS09	Signal Word	Danger

Use of Benzo[e]pyrene

Benzo[e]pyrene occurs in fossil fuels and is a highly toxic member of a family of compounds called polyaromatic hydrocarbons (PAHs)[1].

Name	benzo[e]pyrene
Synonym	More Synonyms

Description	Benzo[e]pyrene occurs in fossil fuels and is a highly toxic member of a family of compounds called polyaromatic hydrocarbons (PAHs)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Schwarz FP, et al Fluorescence measurements of benzene, naphthalene, anthracene, pyrene, fluoranthene, and benzo(e)pyrene in water. Anal Chem. 1976 Mar;48(3):524-8

Density	1.3±0.1 g/cm3
Boiling Point	467.5±12.0 °C at 760 mmHg
Melting Point	177-180ºC(lit.)
Molecular Formula	C₂₀H₁₂
Molecular Weight	252.309
Flash Point	228.6±13.7 °C
Exact Mass	252.093903
LogP	6.40
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.887

Benzo[e]pyrene MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DJ4200000

CHEMICAL NAME :: Benzo(e)pyrene

CAS REGISTRY NUMBER :: 192-97-2

BEILSTEIN REFERENCE NO. :: 1911334

LAST UPDATED :: 199710

DATA ITEMS CITED :: 40

MOLECULAR FORMULA :: C20-H12

MOLECULAR WEIGHT :: 252.32

WISWESSER LINE NOTATION :: L D6666 B6 2AB TJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 360 mg/kg/43W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 240 mg/kg/30W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 160 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - facilitates action of known carcinogen

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 140 mg/kg/37W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - facilitates action of known carcinogen

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 516 mg/kg/43W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 300 mg/kg

SEX/DURATION :: female 8 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 150 mg/kg

SEX/DURATION :: female 8 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: DNA adduct

TYPE OF TEST :: Sister chromatid exchange

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 1 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 53,284,1978 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 3,137,1973 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,225,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,225,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Symbol	GHS08, GHS09
Signal Word	Danger
Hazard Statements	H350-H410
Precautionary Statements	P201-P273-P308 + P313-P501
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T,N,Xn,F
Risk Phrases	45-50/53-67-65-38-11
Safety Phrases	S45;S53;S60;S61;S36/S37/S39
RIDADR	UN 3077 9/PG 3
WGK Germany	3
RTECS	DJ4200000
Packaging Group	III
Hazard Class	6.1(b)

Precursor 8
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DownStream 2
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Benzo[e]pyrene
Price: ￥1078.0/10mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Benzo[e]pyrene
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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