PHGDH-inactive

Modify Date: 2024-01-14 12:09:09

PHGDH-inactive Structure
PHGDH-inactive structure
Common Name PHGDH-inactive
CAS Number 1914971-16-6 Molecular Weight 327.447
Density 1.3±0.1 g/cm3 Boiling Point 497.9±55.0 °C at 760 mmHg
Molecular Formula C17H21N5S Melting Point N/A
MSDS N/A Flash Point 254.9±31.5 °C

 Use of PHGDH-inactive


PHGDH-inactive has no activity against PHGDH and serves as a negative control of NCT-502 and NCT-503[1].

 Names

Name PHGDH-inactive
Synonym More Synonyms

 PHGDH-inactive Biological Activity

Description PHGDH-inactive has no activity against PHGDH and serves as a negative control of NCT-502 and NCT-503[1].
Related Catalog
In Vitro PHGDH-inactive has no activity against PHGDH and serves as a negative control[1].
References

[1]. Pacold ME, et al. A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate [published correction appears in Nat Chem Biol. 2016 Jul 19;12 (8):656]. Nat Chem Biol. 2016;12(6):452-458.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 497.9±55.0 °C at 760 mmHg
Molecular Formula C17H21N5S
Molecular Weight 327.447
Flash Point 254.9±31.5 °C
Exact Mass 327.151764
LogP 0.82
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.674

 Synonyms

PHGDH-inactive
N-(4,6-Dimethylpyridin-2-yl)-4-(pyridin-4-yl)piperazine-1-carbothioamide
1-Piperazinecarbothioamide, N-(4,6-dimethyl-2-pyridinyl)-4-(4-pyridinyl)-
NCT-503 Inactive Control
N-(4,6-Dimethyl-2-pyridinyl)-4-(4-pyridinyl)-1-piperazinecarbothioamide