1914971-16-6

1914971-16-6 structure

Name: PHGDH-inactive
Chemical Name: PHGDH-inactive
CAS Number: 1914971-16-6
Molecular Formula: C₁₇H₂₁N₅S
Molecular Weight: 327.447
Catalog: Research Areas Cancer
Create Date: 2021-01-09 19:54:46
Modify Date: 2025-08-27 16:55:10
PHGDH-inactive has no activity against PHGDH and serves as a negative control of NCT-502 and NCT-503[1].

Name	PHGDH-inactive
Synonyms	PHGDH-inactive N-(4,6-Dimethylpyridin-2-yl)-4-(pyridin-4-yl)piperazine-1-carbothioamide 1-Piperazinecarbothioamide, N-(4,6-dimethyl-2-pyridinyl)-4-(4-pyridinyl)- NCT-503 Inactive Control N-(4,6-Dimethyl-2-pyridinyl)-4-(4-pyridinyl)-1-piperazinecarbothioamide

Description	PHGDH-inactive has no activity against PHGDH and serves as a negative control of NCT-502 and NCT-503[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	PHGDH-inactive has no activity against PHGDH and serves as a negative control[1].
References	[1]. Pacold ME, et al. A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate [published correction appears in Nat Chem Biol. 2016 Jul 19;12 (8):656]. Nat Chem Biol. 2016;12(6):452-458.