PHGDH-inactive

Names

[ CAS No. ]:
1914971-16-6

[ Name ]:
PHGDH-inactive

[Synonym ]:
PHGDH-inactive
N-(4,6-Dimethylpyridin-2-yl)-4-(pyridin-4-yl)piperazine-1-carbothioamide
1-Piperazinecarbothioamide, N-(4,6-dimethyl-2-pyridinyl)-4-(4-pyridinyl)-
NCT-503 Inactive Control
N-(4,6-Dimethyl-2-pyridinyl)-4-(4-pyridinyl)-1-piperazinecarbothioamide

Biological Activity

[Description]:

PHGDH-inactive has no activity against PHGDH and serves as a negative control of NCT-502 and NCT-503[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

PHGDH-inactive has no activity against PHGDH and serves as a negative control[1].

[References]

[1]. Pacold ME, et al. A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate [published correction appears in Nat Chem Biol. 2016 Jul 19;12 (8):656]. Nat Chem Biol. 2016;12(6):452-458.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
497.9±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₂₁N₅S

[ Molecular Weight ]:
327.447

[ Flash Point ]:
254.9±31.5 °C

[ Exact Mass ]:
327.151764

[ LogP ]:
0.82

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.674

Related Compounds

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