Ezurpimtrostat hydrochloride

Modify Date: 2024-01-02 11:53:03

Ezurpimtrostat hydrochloride Structure
Ezurpimtrostat hydrochloride structure
Common Name Ezurpimtrostat hydrochloride
CAS Number 1914148-73-4 Molecular Weight 459.45
Density N/A Boiling Point N/A
Molecular Formula C25H32Cl2N4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ezurpimtrostat hydrochloride


Ezurpimtrostat hydrochloride (compound 2-3) is a potent and orally active anti-fibrotic agent. Ezurpimtrostat hydrochloride reduces significantly the liver fibrosis in DEN (diethyl nitrosamine) cirrhotic rat model. Ezurpimtrostat hydrochloride can be used for the research of fibrosis, cancer, autophagy and cathepsins B (CTSB), L (CTSL) and D (CTSD) related diseases [1].

 Names

Name Ezurpimtrostat hydrochloride

 Ezurpimtrostat hydrochloride Biological Activity

Description Ezurpimtrostat hydrochloride (compound 2-3) is a potent and orally active anti-fibrotic agent. Ezurpimtrostat hydrochloride reduces significantly the liver fibrosis in DEN (diethyl nitrosamine) cirrhotic rat model. Ezurpimtrostat hydrochloride can be used for the research of fibrosis, cancer, autophagy and cathepsins B (CTSB), L (CTSL) and D (CTSD) related diseases [1].
Related Catalog
In Vivo Ezurpimtrostat hydrochloride (compound 2-3) (15 mg/kg/day, PO, for 6 weeks) significantly reduces the area of liver fibrosis and the level of collagen fibers deposition (by 41.0%) in DEN cirrhotic rat model[1].
References

[1]. Philippe Halfon, et al. Substituted 2,4 diamino-quinoline as new medicament for fibrosis, autophagy and cathepsins b (ctsb), l (ctsl) and d (ctsd) related diseases. EP3620164A1.

 Chemical & Physical Properties

Molecular Formula C25H32Cl2N4
Molecular Weight 459.45
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