7-aminocoumarin

Modify Date: 2024-01-02 17:38:12

7-aminocoumarin Structure
7-aminocoumarin structure
Common Name 7-aminocoumarin
CAS Number 19063-57-1 Molecular Weight 161.157
Density 1.4±0.1 g/cm3 Boiling Point 381.4±37.0 °C at 760 mmHg
Molecular Formula C9H7NO2 Melting Point 207-210°C (lit.)
MSDS N/A Flash Point 219.3±24.0 °C

 Use of 7-aminocoumarin


7-Aminocoumarin is a pH-insensitive blue fluorophore. 7-Aminocoumarin is widely used as laser dyes in the blue-green region. 7-Aminocoumarin can be used to tag recombinant proteins on the cell surface and inside living cells through PRIME (probe incorporation mediated by enzymes). 7-Aminocoumarin can be visualized in acidic organelles such as endosomes[1][2].

 Names

Name 7-aminochromen-2-one
Synonym More Synonyms

 7-aminocoumarin Biological Activity

Description 7-Aminocoumarin is a pH-insensitive blue fluorophore. 7-Aminocoumarin is widely used as laser dyes in the blue-green region. 7-Aminocoumarin can be used to tag recombinant proteins on the cell surface and inside living cells through PRIME (probe incorporation mediated by enzymes). 7-Aminocoumarin can be visualized in acidic organelles such as endosomes[1][2].
Related Catalog
References

[1]. Jin X, et al. Synthesis of 7-aminocoumarin by Buchwald-Hartwig cross coupling for specific protein labeling in living cells. Chembiochem. 2011 Jan 3;12(1):65-70.

[2]. Pedone A. Role of Solvent on Charge Transfer in 7-Aminocoumarin Dyes: New Hints from TD-CAM-B3LYP and State Specific PCM Calculations. J Chem Theory Comput. 2013 Sep 10;9(9):4087-96.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 381.4±37.0 °C at 760 mmHg
Melting Point 207-210°C (lit.)
Molecular Formula C9H7NO2
Molecular Weight 161.157
Flash Point 219.3±24.0 °C
Exact Mass 161.047684
PSA 56.23000
LogP 0.09
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.659
Storage condition -20°C

 Safety Information

Hazard Codes Xi
HS Code 2932209090

 Synthetic Route

~89%

7-aminocoumarin Structure

7-aminocoumarin

CAS#:19063-57-1

Literature: Lin, Shaw-Tao; Yang, Fu-May; Yang, Heuy-Ju; Huang, Keh-Feng Journal of Chemical Research, Synopses, 1995 , # 9 p. 372 - 373

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7-aminocoumarin Structure

7-aminocoumarin

CAS#:19063-57-1

Literature: Yu, Jianzhong; Wang, Yongtao; Zhang, Peizhi; Wu, Jun Synlett, 2013 , vol. 24, # 11 art. no. ST-2013-W0237-L, p. 1448 - 1454

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7-aminocoumarin Structure

7-aminocoumarin

CAS#:19063-57-1

Literature: Journal of Chemical Research, Synopses, , # 9 p. 372 - 373

~%

7-aminocoumarin Structure

7-aminocoumarin

CAS#:19063-57-1

Literature: Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 232, p. 2027

 Customs

HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

7-Amino-2H-chromen-2-one
2H-1-Benzopyran-2-one, 7-amino-
7-Amino-2H-1-benzopyran-2-one
7-aminocoumarin
2H-1-Benzopyran-2-one,7-amino
7-amino coumarin
7-amino-chromen-2-one
7-Amino-cumarin