D-Glucose-d2

Modify Date: 2024-01-02 15:29:01

D-Glucose-d2 Structure
D-Glucose-d2 structure
Common Name D-Glucose-d2
CAS Number 18991-62-3 Molecular Weight 182.168
Density 1.7±0.1 g/cm3 Boiling Point 410.8±45.0 °C at 760 mmHg
Molecular Formula C6H10D2O6 Melting Point 150-152ºC(lit.)
MSDS Chinese USA Flash Point 202.2±28.7 °C

 Use of D-Glucose-d2


D-Glucose-d2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

 Names

Name D-Glucose-6,6-d2
Synonym More Synonyms

 D-Glucose-d2 Biological Activity

Description D-Glucose-d2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 410.8±45.0 °C at 760 mmHg
Melting Point 150-152ºC(lit.)
Molecular Formula C6H10D2O6
Molecular Weight 182.168
Flash Point 202.2±28.7 °C
Exact Mass 182.075943
PSA 110.38000
LogP -1.88
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.635

 Safety Information

RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~83%

D-Glucose-d2 Structure

D-Glucose-d2

CAS#:18991-62-3

Literature: Hammerschmidt, Friedrich Liebigs Annalen der Chemie, 1988 , p. 531 - 536

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D-Glucose-d2 Structure

D-Glucose-d2

CAS#:18991-62-3

Literature: Liebigs Annalen der Chemie, , p. 531 - 536

~%

D-Glucose-d2 Structure

D-Glucose-d2

CAS#:18991-62-3

Literature: Carbohydrate Research, , vol. 95, p. 1 - 26

 Articles1

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 Synonyms

Dextrose-6,6-d2
(3R,4S,5S,6R)-6-[dideuterio(hydroxy)methyl]oxane-2,3,4,5-tetrol
Deuterated Glucose,Dextrose-6,6-d2,Labeled Glucose
MFCD00064367
D-Glucopyranose-C,C-d
D-(C,C-H)Glucopyranose