MT16-205
Modify Date: 2023-01-14 22:09:37
MT16-205 structure
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Common Name | MT16-205 | ||
|---|---|---|---|---|
| CAS Number | 1895051-79-2 | Molecular Weight | 322.386 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H14N4Os | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MT16-205MT16-205 (MT 16-205) is a potent, selective, covalent UCHL1 inhibitor with IC50 of 600 nM, no inhibition agianst UCHL3 (IC50>10 uM).MT16-205 inhibited both UCHL1 and the structurally unrelated DUB USP30 with similar potency.MT16-205 displayed cell proliferation cytotoxicity in human embryonic kidney cells (HEK293) with IC50 of 350 nM, MT16-205 effectively engaged UCHL1 in cells with IC50 of 830 nM. |
| Name | MT16-205 |
|---|
| Description | MT16-205 (MT 16-205) is a potent, selective, covalent UCHL1 inhibitor with IC50 of 600 nM, no inhibition agianst UCHL3 (IC50>10 uM).MT16-205 inhibited both UCHL1 and the structurally unrelated DUB USP30 with similar potency.MT16-205 displayed cell proliferation cytotoxicity in human embryonic kidney cells (HEK293) with IC50 of 350 nM, MT16-205 effectively engaged UCHL1 in cells with IC50 of 830 nM. |
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| References | 1. Nattawadee Panyain, et al. RSC Med Chem. 2021 Aug 16;12(11):1935-1943. |
| Molecular Formula | C17H14N4Os |
|---|---|
| Molecular Weight | 322.386 |