AP-1/NF-κB activation inhibitor 1

Modify Date: 2024-01-14 20:55:23

AP-1/NF-κB activation inhibitor 1 structure	Common Name	AP-1/NF-κB activation inhibitor 1
	CAS Number	188936-12-1	Molecular Weight	344.25
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₁₁F₃N₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AP-1/NF-κB activation inhibitor 1

AP-1/NF-κB activation inhibitor 1 is a potent AP-1 and NF-κB mediated transcriptional activation inhibitor (IC50=1 μM), without blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation inhibitor 1 has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells[1].

Name	AP-1/NF-κB activation inhibitor 1

Description	AP-1/NF-κB activation inhibitor 1 is a potent AP-1 and NF-κB mediated transcriptional activation inhibitor (IC50=1 μM), without blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation inhibitor 1 has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells[1].
Related Catalog	Research Areas >> Inflammation/Immunology
References	[1]. Palanki MS, et al. Novel inhibitors of AP-1 and NF-kappaB mediated gene expression: structure-activity relationship studies of ethyl 4-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)++ +pyrimidi ne-5-carboxylate. Bioorg Med Chem Lett. 2000;10(15):1645-1648.

Molecular Formula	C₁₃H₁₁F₃N₄O₄
Molecular Weight	344.25

DC Chemicals Limited
China
Product Name: AP-1/NF-κB activation inhibitor 1
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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