Salicortin

Modify Date: 2025-08-26 22:01:29

Salicortin Structure
Salicortin structure
Common Name Salicortin
CAS Number 1887055-63-1 Molecular Weight 424.40
Density N/A Boiling Point N/A
Molecular Formula C20H24O10 Melting Point 141-142 °C
MSDS N/A Flash Point N/A

 Use of Salicortin


Salicortin, a phenolic glycoside, has been isolated from many plants such as Populus and Salix species. Salicortin inhibits osteoclast differentiation and bone resorption by down-regulating JNK and NF-κB/NFATc1 signaling pathways. Salicortin has anti-amnesic, anti-adipogenic, and immune-modulatory activity[1].

 Names

Name Salicortin
Synonym More Synonyms

 Salicortin Biological Activity

Description Salicortin, a phenolic glycoside, has been isolated from many plants such as Populus and Salix species. Salicortin inhibits osteoclast differentiation and bone resorption by down-regulating JNK and NF-κB/NFATc1 signaling pathways. Salicortin has anti-amnesic, anti-adipogenic, and immune-modulatory activity[1].
Related Catalog
Target

JNK

NF-κB

In Vitro Salicortin (100 μM; 2 hours) almost completely retards the phosphorylation of IκBα[1]. Western Blot Analysis[1] Cell Line: Mouse bone marrow macrophage (BMM) Concentration: 100 μM Incubation Time: 2 hours Result: Retarded the phosphorylation of IκBα.
References

[1]. Nie S, et al. Salicortin inhibits osteoclast differentiation and bone resorption by down-regulating JNK and NF-κB/NFATc1 signaling pathways. Biochem Biophys Res Commun. 2016 Jan 29;470(1):61-67.

 Chemical & Physical Properties

Melting Point 141-142 °C
Molecular Formula C20H24O10
Molecular Weight 424.40

 Synonyms

MFCD32202744
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