(-)-catechin

Modify Date: 2024-01-07 16:29:26

(-)-catechin Structure
(-)-catechin structure
Common Name (-)-catechin
CAS Number 18829-70-4 Molecular Weight 290.26800
Density 1.593 g/cm3 Boiling Point 630.4ºC at 760 mmHg
Molecular Formula C15H14O6 Melting Point 175-176ºC
MSDS Chinese USA Flash Point 335ºC

 Use of (-)-catechin


(-)-Catechin, isolated from green tea, is an isomer of Catechin having a trans 2S,3R configuration at the chiral center. Catechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.

 Names

Name (-)-catechin
Synonym More Synonyms

 (-)-catechin Biological Activity

Description (-)-Catechin, isolated from green tea, is an isomer of Catechin having a trans 2S,3R configuration at the chiral center. Catechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
Related Catalog
References

[1]. Waffo-Téguo P, et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40(2):173-9.

 Chemical & Physical Properties

Density 1.593 g/cm3
Boiling Point 630.4ºC at 760 mmHg
Melting Point 175-176ºC
Molecular Formula C15H14O6
Molecular Weight 290.26800
Flash Point 335ºC
Exact Mass 290.07900
PSA 110.38000
LogP 1.54610
Vapour Pressure 1.09E-20mmHg at 25°C
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles11

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An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.

J. Nat. Prod. 73 , 1193-5, (2010)

Antioxidants scavenge free radicals, singlet oxygen, and electrons in cellular redox reactions. The yellow MTT [3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide] is reduced to a purple fo...

The blood pressure effect and related plasma levels of flavan-3-ols in spontaneously hypertensive rats.

Food Funct. 6 , 3479-89, (2015)

We studied the short-term antihypertensive effect of flavan-3-ols (-)-epicatechin, (+)-catechin and (-)-catechin, in spontaneously hypertensive rats (SHR). Plasma metabolites and the corresponding pla...

Galactolipids from Bauhinia racemosa as a new class of antifilarial agents against human lymphatic filarial parasite, Brugia malayi.

Eur. J. Med. Chem. 50 , 230-5, (2012)

Bioassay guided fractionation of ethanolic extract of the leaves of Bauhinia racemosa led to the isolation of galactolipid and catechin class of the compounds (1-7) from the most active n-butanol frac...

 Synonyms

ent-catechin
(2S,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
MFCD00180760
(-)-Catechin
EINECS 242-611-7
(−)-Catechin
Catechin l-form