ER 50891

Modify Date: 2024-04-03 10:27:11

ER 50891 Structure
ER 50891 structure
Common Name ER 50891
CAS Number 187400-85-7 Molecular Weight 432.51300
Density N/A Boiling Point N/A
Molecular Formula C29H24N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ER 50891


ER-50891 is a potent antagonist of retinoic acid receptor α(RARα). ER-50891 significantly attenuates ATRA's inhibitive effects on BMP 2-induced osteoblastogenesis[1].

 Names

Name 4-[5-(8-Isopropyl-4-phenyl-2-quinolinyl)-1H-pyrrol-2-yl]benzoic a cid

 ER 50891 Biological Activity

Description ER-50891 is a potent antagonist of retinoic acid receptor α(RARα). ER-50891 significantly attenuates ATRA's inhibitive effects on BMP 2-induced osteoblastogenesis[1].
Related Catalog
Target

RARα[1]

References

[1]. Batran RZ, et al. New quinolone derivatives as neuropeptide S receptor antagonists: Design, synthesis, homology modeling, dynamic simulations and modulation of Gq/Gs signaling pathways. Bioorg Chem. 2021;111:104817.

 Chemical & Physical Properties

Molecular Formula C29H24N2O2
Molecular Weight 432.51300
Exact Mass 432.18400
PSA 65.98000
LogP 7.38550
Top Suppliers:I want be here


Get all suppliers and price by the below link:

ER 50891 suppliers

ER 50891 price

Related Compounds: More...
ER-Tracker Green
730931-46-1
ER D8
51554-93-9
er-878705
102554-82-5
er(fod)3
17978-75-5
ER degrader 1
2667015-33-8
(2-{(2R,6R)-6-[(2S)-4-(Bromomethyl)-2-methylpent-4-enyl]-5,6-dihydro-2H-pyran-2-yl}ethoxy)(tert-butyl)dimethylsilane
362471-69-0
ER-001259851-000
2685738-33-2
ER 27319 maleate
1204480-26-1
ER proteostasis regulator-1
912777-95-8
Benzenesulfonic acid, 3,3a(2)-[(2-chloro-5-ethyl-3,6-dioxo-1,4-cyclohexadiene-1,4-diyl)diimino]bis[6-[(2-aminoethyl)amino]-
157246-20-3
1-[(2-Chloro-4-fluorophenyl)methyl]-4-piperidinecarboxylic acid 2-[[3-[(2-thienylcarbonyl)oxy]phenyl]methylene]hydrazide
884130-12-5
Ethyl 2-[[(hexahydro-2,5-methanopentalen-3a(1H)-yl)carbonyl]amino]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-3-carboxylate
1101856-89-6
tert-butyl 2-(6-(3-((tert-butoxycarbonyl)amino)prop-1-yn-1-yl)-1H-indazol-3-yl)-1H-pyrrole-1-carboxylate
1206454-50-3
2-[2-[5-Hydroxy-1-[4-[(2-hydroxyethyl)sulfonyl]phenyl]-3-methyl-1H-pyrazol-4-yl]diazenyl]-1,5-naphthalenedisulfonic acid
1178555-75-3
Spiro[2-azabicyclo[2.2.1]heptane-7,2a(2)-pyrrolidine]-2-carboxylic acid, 5a(2)-oxo-, 1,1-dimethylethyl ester, (1R,2a(2)S,4R)-rel-
1251013-81-6
Hexahydro-2,2-dimethyl-9-(phenylmethyl)-4,12-epoxy-5H-1,3-dioxolo[4,5-f]pyrimido[1,6-a][1,3]diazocine-8,10(6H,7H)-dione
61210-25-1
Benzeneacetic acid, 3-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-I+/--[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (I+/-S)-
1251904-03-6
5,11-Epoxy-6,9-methano-5H-cyclohepta[b]naphthalene, 6,7,8,9,10,11-hexahydro-10,10-dimethyl-5,11-diphenyl-, stereoisomer
913-32-6
4-Methoxyphenyl (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
900500-26-7