ER 50891

Names

[ Name ]:
ER 50891

Biological Activity

[Description]:

ER-50891 is a potent antagonist of retinoic acid receptor α(RARα). ER-50891 significantly attenuates ATRA's inhibitive effects on BMP 2-induced osteoblastogenesis[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> RAR/RXR

[Target]

RARα[1]

[References]

[1]. Batran RZ, et al. New quinolone derivatives as neuropeptide S receptor antagonists: Design, synthesis, homology modeling, dynamic simulations and modulation of Gq/Gs signaling pathways. Bioorg Chem. 2021;111:104817.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₂₄N₂O₂

[ Molecular Weight ]:
432.51300

[ Exact Mass ]:
432.18400

[ PSA ]:
65.98000

[ LogP ]:
7.38550

Related Compounds

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