2-NBDG

Modify Date: 2024-01-09 17:44:31

2-NBDG Structure
2-NBDG structure
Common Name 2-NBDG
CAS Number 186689-07-6 Molecular Weight 342.262
Density 1.750±0.06 g/cm3 Boiling Point 707.6±70.0 °C at 760 mmHg
Molecular Formula C12H14N4O8 Melting Point N/A
MSDS USA Flash Point 381.7±35.7 °C

 Use of 2-NBDG


2-NBDG is a fluorescent indicator for direct glucose uptake measurement and also is an indicator of cell viability.

 Names

Name 2-NBDG
Synonym More Synonyms

 2-NBDG Biological Activity

Description 2-NBDG is a fluorescent indicator for direct glucose uptake measurement and also is an indicator of cell viability.
Related Catalog
References

[1]. Zou C, et al. 2-NBDG as a fluorescent indicator for direct glucose uptake measurement. J Biochem Biophys Methods. 2005 Sep 30;64(3):207-15.

 Chemical & Physical Properties

Density 1.750±0.06 g/cm3
Boiling Point 707.6±70.0 °C at 760 mmHg
Molecular Formula C12H14N4O8
Molecular Weight 342.262
Flash Point 381.7±35.7 °C
Exact Mass 342.081177
PSA 186.92000
LogP -0.41
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.770
Storage condition 2-8℃
Water Solubility Very slightly soluble (0.48 g/L) (25 ºC)

 Safety Information

RIDADR NONH for all modes of transport

 Articles78

More Articles
Targeting glucose uptake with siRNA-based nanomedicine for cancer therapy.

Biomaterials 51 , 1-11, (2015)

Targeting cancer metabolism is emerging as a successful strategy for cancer therapy. However, most of the marketed anti-metabolism drugs in cancer therapy do not distinguish normal cells from cancer c...

Preconditioning L6 Muscle Cells with Naringin Ameliorates Oxidative Stress and Increases Glucose Uptake.

PLoS ONE 10 , e0132429, (2015)

Enhanced oxidative stress contributes to pathological changes in diabetes and its complications. Thus, strategies to reduce oxidative stress may alleviate these pathogenic processes. Herein, we have i...

Redox-based probes as tools to monitor oxidized protein tyrosine phosphatases in living cells.

Eur. J. Med. Chem. 88 , 28-33, (2014)

Reversible oxidation of protein tyrosine phosphatases (PTPs) has emerged as an important regulatory mechanism whereby reactive oxygen species (ROS) inactivates the PTP and promotes phosphorylation and...

 Synonyms

2-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-D-glucose
D-Glucose, 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-
2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose
D-Glucopyranose, 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-
2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucopyranose