Fosmetpantotenate

Modify Date: 2025-08-21 19:43:46

Fosmetpantotenate structure	Common Name	Fosmetpantotenate
	CAS Number	1858268-66-2	Molecular Weight	474.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₃₁N₂O₉P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Fosmetpantotenate

Fosmetpantotenate is a phosphopantothenic acid (PPA) prodrug designed to release PPA intracellularly, leading to restoration of CoA levels. Fosmetpantotenate is used to treat pantothenate kinase-associated neurodegeneration.

Name	Fosmetpantotenate

Description	Fosmetpantotenate is a phosphopantothenic acid (PPA) prodrug designed to release PPA intracellularly, leading to restoration of CoA levels. Fosmetpantotenate is used to treat pantothenate kinase-associated neurodegeneration.
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Elbaum D, Beconi MG, Monteagudo E, et al. Fosmetpantotenate (RE-024), a phosphopantothenate replacement therapy for pantothenate kinase-associated neurodegeneration: Mechanism of action and efficacy in nonclinical models. PLoS One. 2018;13(3):e0192028. Published 2018 Mar 9. [2]. Klopstock T, Escolar ML, Marshall RD, et al. The FOsmetpantotenate Replacement Therapy (FORT) randomized, double-blind, Placebo-controlled pivotal trial: Study design and development methodology of a novel primary efficacy outcome in patients with pantothenate kinase-associated neurodegeneration. Clin Trials. 2019;16(4):410-418.

Description

Related Catalog

Research Areas >> Neurological Disease

References

[1]. Elbaum D, Beconi MG, Monteagudo E, et al. Fosmetpantotenate (RE-024), a phosphopantothenate replacement therapy for pantothenate kinase-associated neurodegeneration: Mechanism of action and efficacy in nonclinical models. PLoS One. 2018;13(3):e0192028. Published 2018 Mar 9.

[2]. Klopstock T, Escolar ML, Marshall RD, et al. The FOsmetpantotenate Replacement Therapy (FORT) randomized, double-blind, Placebo-controlled pivotal trial: Study design and development methodology of a novel primary efficacy outcome in patients with pantothenate kinase-associated neurodegeneration. Clin Trials. 2019;16(4):410-418.

Molecular Formula	C₂₀H₃₁N₂O₉P
Molecular Weight	474.44

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Fosmetpantotenate

Use of Fosmetpantotenate

Names

Fosmetpantotenate Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.