DS-1205b free base

Modify Date: 2025-08-25 12:30:44

DS-1205b free base Structure
DS-1205b free base structure
Common Name DS-1205b free base
CAS Number 1855860-24-0 Molecular Weight 735.80
Density N/A Boiling Point N/A
Molecular Formula C41H42FN5O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DS-1205b free base


DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo.

 Names

Name DS-1205b free base

 DS-1205b free base Biological Activity

Description DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo.

 Chemical & Physical Properties

Molecular Formula C41H42FN5O7
Molecular Weight 735.80
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