TAS4464 hydrochloride

Modify Date: 2024-01-11 10:21:31

TAS4464 hydrochloride Structure
TAS4464 hydrochloride structure
Common Name TAS4464 hydrochloride
CAS Number 1848959-11-4 Molecular Weight 542.97
Density N/A Boiling Point N/A
Molecular Formula C21H24ClFN6O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TAS4464 hydrochloride


TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM[1].

 Names

Name TAS4464 hydrochloride
Synonym More Synonyms

 TAS4464 hydrochloride Biological Activity

Description TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM[1].
Related Catalog
Target

IC50:0.955 nM (NAE)[1]

References

[1]. Yoshimura C, et al. TAS4464, a highly potent and selective inhibitor of NEDD8 activating enzyme, suppresses neddylation and shows antitumor activity in diverse cancer models. Mol Cancer Ther. 2019 May 15.

 Chemical & Physical Properties

Molecular Formula C21H24ClFN6O6S
Molecular Weight 542.97

 Synonyms

MFCD32067968
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