Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TAS4464 hydrochloride
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
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1848959-11-4

1848959-11-4 structure

1848959-11-4 structure

Name: TAS4464 hydrochloride
Chemical Name: TAS4464 hydrochloride
CAS Number: 1848959-11-4
Molecular Formula: C₂₁H₂₄ClFN₆O₆S
Molecular Weight: 542.97
Catalog: Signaling Pathways Metabolic Enzyme/Protease NEDD8-activating Enzyme
Create Date: 2019-06-30 06:50:05
Modify Date: 2025-08-27 19:48:20
TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM[1].

Name	TAS4464 hydrochloride
Synonyms	MFCD32067968

Description	TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> NEDD8-activating Enzyme
Target	IC50：0.955 nM (NAE)[1]
References	[1]. Yoshimura C, et al. TAS4464, a highly potent and selective inhibitor of NEDD8 activating enzyme, suppresses neddylation and shows antitumor activity in diverse cancer models. Mol Cancer Ther. 2019 May 15.

Molecular Formula	C₂₁H₂₄ClFN₆O₆S
Molecular Weight	542.97

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