(−)-Myrtenal

Modify Date: 2024-01-03 17:28:57

(−)-Myrtenal Structure
(−)-Myrtenal structure
Common Name (−)-Myrtenal
CAS Number 18486-69-6 Molecular Weight 150.22
Density 0.988 g/mL at 20ºC(lit.) Boiling Point 220-221ºC(lit.)
Molecular Formula C10H14O Melting Point N/A
MSDS Chinese USA Flash Point 174 °F

 Use of (−)-Myrtenal


(−)-Myrtenal ((1R)-(−)-Myrtenal) is an orally active terpene with antitumour activity. (−)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats[1][2].

 Names

Name (-)-myrtenal
Synonym More Synonyms

 (−)-Myrtenal Biological Activity

Description (−)-Myrtenal ((1R)-(−)-Myrtenal) is an orally active terpene with antitumour activity. (−)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats[1][2].
Related Catalog
In Vitro (−)-Myrtenal ((1R)-(−)-Myrtenal; 0.1-5 mM; for 24 h) exerts strong cytotoxic effect (IC50 = 5.3 mM) on human colon tumour (HT29) and human normal colon epithelial cells (CCD 841 CoTr)[1].
In Vivo (−)-Myrtenal ((1R)-(−)-Myrtenal; orally; 80 mg/kg/day for 28 days) reveals decreased the levels of plasma glucose, improved the plasma insulin levels, up-regulation of IRS2, Akt and GLUT2 in liver and IRS2, Akt and GLUT4 protein expression in skeletal muscle in diabetic rats induced by single intraperitoneal injection of Streptozotocin (STZ) (40 mg/kg bw)[2].
References

[1]. Mariusz Trytek, et al. Biological activity of oxygenated pinene derivatives on human colon normal and carcinoma cells. Flavour and Fragrance Journal, Volume33, Issue6, November 2018.

[2]. Ayyasamy Rathinam, et al. Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats. Chem Biol Interact. 2016 Aug 25;256:161-6.

 Chemical & Physical Properties

Density 0.988 g/mL at 20ºC(lit.)
Boiling Point 220-221ºC(lit.)
Molecular Formula C10H14O
Molecular Weight 150.22
Flash Point 174 °F
Exact Mass 150.10400
PSA 17.07000
LogP 2.17770
Appearance of Characters Liquid | Clear colorless to yellow
Index of Refraction n20/D 1.504
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves
Safety Phrases 23-24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS DT5180000

 Articles7

More Articles
Synthesis of stable thromboxane A2 analogs: pinane thromboxane A2 (PTA2) and carbocyclic thromboxane A2 (CTA2).

Meth. Enzymol. 86 , 400, (1982)

Organoleptic Characteristics of Flavor Materials Mosciano, G.

Perfum. Flavor. 8th ed., 30 , 41, (2005)

Mosciano, G.

Perfum. Flavor. 7th ed., 30 , 56, (2005)

 Synonyms

(1R,5S)-6,6-dimethyl-bicyclo[3.3.1]hept-2-en-2-carbaldehyde
FEMA 3395
l-Myrtenal
(R)-6,6-dimethylbicyclo[3.3.1]hept-2-en-2-carboxaldehyde
(-)-(1R,5S)-Myrtenal
(-)-Myrtenal
(1R)-6,6-DIMETHYLBICYCLO[3.1.1]HEPT-2-EN-2-CARBOXAL-DEHYDE
(-)-1R-6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-carboxaldehyde
(1R)-2-PINEN-10-AL
MYRTENAL,-(-)-(SG)
(R)-mirtenal
MYRTENAL,-(-)
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