CL2A

Modify Date: 2025-08-24 19:04:32

CL2A Structure
CL2A structure
Common Name CL2A
CAS Number 1846605-04-6 Molecular Weight 1106.22
Density N/A Boiling Point N/A
Molecular Formula C51H79N9O18 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CL2A


CL2A is a complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker[1].

 Names

Name CL2A

 CL2A Biological Activity

Description CL2A is a complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker[1].
Related Catalog
Target

Alkyl/ether

References

[1]. Samantha Congreve, et al. Antibody drug conjugates (ADC). Teknisk- naturvetenskaplig fakultet

 Chemical & Physical Properties

Molecular Formula C51H79N9O18
Molecular Weight 1106.22
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.