2-Amino-6-picoline

Modify Date: 2024-01-02 17:34:17

2-Amino-6-picoline Structure
2-Amino-6-picoline structure
Common Name 2-Amino-6-picoline
CAS Number 1824-81-3 Molecular Weight 108.141
Density 1.1±0.1 g/cm3 Boiling Point 208.5±0.0 °C at 760 mmHg
Molecular Formula C6H8N2 Melting Point 40-44 °C(lit.)
MSDS Chinese USA Flash Point 103.3±0.0 °C
Symbol GHS06
GHS06
Signal Word Danger

 Names

Name 6-methylpyridin-2-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 208.5±0.0 °C at 760 mmHg
Melting Point 40-44 °C(lit.)
Molecular Formula C6H8N2
Molecular Weight 108.141
Flash Point 103.3±0.0 °C
Exact Mass 108.068748
PSA 38.91000
LogP 1.08
Vapour Pressure 0.2±0.4 mmHg at 25°C
Index of Refraction 1.574

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US1885000
CHEMICAL NAME :
Pyridine, 2-amino-6-methyl-
CAS REGISTRY NUMBER :
1824-81-3
BEILSTEIN REFERENCE NO. :
0107048
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C6-H8-N2
MOLECULAR WEIGHT :
108.16
WISWESSER LINE NOTATION :
T6NJ BZ F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,841,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
52 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
REFERENCE :
AJEBAK Australian Journal of Experimental Biology and Medical Science. (Adelaide, S.A., Australia) V.1-64, 1924-86. Volume(issue)/page/year: 36,491,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
18 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00148
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,841,1986

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H310-H315-H319-H335
Precautionary Statements P261-P280-P301 + P310-P302 + P350-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T:Toxic
Risk Phrases R24/25;R36/37/38
Safety Phrases S26-S36/37/39-S45-S37/39-S28A
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS US1885000
Packaging Group II
Hazard Class 6.1
HS Code 29333999

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles1

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New mixed ligand zinc(II) complexes based on the antiepileptic drug sodium valproate and bioactive nitrogen-donor ligands. Synthesis, structure and biological properties.

Eur. J. Med. Chem. 82 , 152-63, (2014)

Starting from the precursor [Zinc Valproate complex] (1), new mixed ligand zinc(II) complexes of valproic acid and nitrogen-based ligands, formulating as, [Zn(valp)22,9-dmphen] (2), [Zn2(valp)4(quin)2...

 Synonyms

6-Methyl-2-aminopyridine
2-amino-6-Me-pyridine
2-Picoline,6-amino
6-Methyl-pyridin-2-ylamine
2-Amino-6-methylpyridine
2-Pyridinamine,6-methyl
6-Methyl-2-pyridylamine
MFCD00006331
6-Methylpyridin-2-amin
2-amino-6-methyl-pyridine
2-Pyridinamine, 6-methyl-
6-Methyl-2-pyridinamine
6-MePy-2-NH2
6-methylpyridin-2-amine
6-Amino-2-picoline
2-Amino-6-picoline
EINECS 217-360-1
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