2-Amino-6-picoline
Names
[ CAS No. ]:
1824-81-3
[ Name ]:
2-Amino-6-picoline
[Synonym ]:
6-Methyl-2-aminopyridine
2-amino-6-Me-pyridine
2-Picoline,6-amino
6-Methyl-pyridin-2-ylamine
2-Amino-6-methylpyridine
2-Pyridinamine,6-methyl
6-Methyl-2-pyridylamine
MFCD00006331
6-Methylpyridin-2-amin
2-amino-6-methyl-pyridine
2-Pyridinamine, 6-methyl-
6-Methyl-2-pyridinamine
6-MePy-2-NH2
6-methylpyridin-2-amine
6-Amino-2-picoline
2-Amino-6-picoline
EINECS 217-360-1
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
208.5±0.0 °C at 760 mmHg
[ Melting Point ]:
40-44 °C(lit.)
[ Molecular Formula ]:
C6H8N2
[ Molecular Weight ]:
108.141
[ Flash Point ]:
103.3±0.0 °C
[ Exact Mass ]:
108.068748
[ PSA ]:
38.91000
[ LogP ]:
1.08
[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.574
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- US1885000
- CHEMICAL NAME :
- Pyridine, 2-amino-6-methyl-
- CAS REGISTRY NUMBER :
- 1824-81-3
- BEILSTEIN REFERENCE NO. :
- 0107048
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C6-H8-N2
- MOLECULAR WEIGHT :
- 108.16
- WISWESSER LINE NOTATION :
- T6NJ BZ F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,841,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 52 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- AJEBAK Australian Journal of Experimental Biology and Medical Science. (Adelaide, S.A., Australia) V.1-64, 1924-86. Volume(issue)/page/year: 36,491,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 18 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00148
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,841,1986
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H310-H315-H319-H335
[ Precautionary Statements ]:
P261-P280-P301 + P310-P302 + P350-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic
[ Risk Phrases ]:
R24/25;R36/37/38
[ Safety Phrases ]:
S26-S36/37/39-S45-S37/39-S28A
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
US1885000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
29333999
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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Starting from the precursor [Zinc Valproate complex] (1), new mixed ligand zinc(II) complexes of valproic acid and nitrogen-based ligands, formulating as, [Zn(valp)22,9-dmphen] (2), [Zn2(valp)4(quin)2...