Ubiquitination-IN-1

Modify Date: 2024-01-16 18:07:26

Ubiquitination-IN-1 structure	Common Name	Ubiquitination-IN-1
	CAS Number	1819330-15-8	Molecular Weight	429.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₄F₃N₃O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Ubiquitination-IN-1

Ubiquitination-IN-1 (compound 24) is a ubiquitination and Cksl-Skp2 protein-protein interaction (IC50=0.17 μM) inhibitor. Ubiquitination-IN-1 increases levels of p27. Ubiquitination-IN-1 can be used to treat disease by blocking the degradation of tumor suppressors[1].

Name	Ubiquitination-IN-1

Description	Ubiquitination-IN-1 (compound 24) is a ubiquitination and Cksl-Skp2 protein-protein interaction (IC50=0.17 μM) inhibitor. Ubiquitination-IN-1 increases levels of p27. Ubiquitination-IN-1 can be used to treat disease by blocking the degradation of tumor suppressors[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> E1/E2/E3 Enzyme
In Vitro	Ubiquitination-IN-1 inhibits A549 and HT1080 cells with IC50s of 0.91 and 0.4 μM, respectively[1].
References	[1]. David Carroll, et al.Quinoline derivatives useful as ubiquitination inhibitors. WO2016025779A1.

Molecular Formula	C₂₁H₁₄F₃N₃O₂S
Molecular Weight	429.41

DC Chemicals Limited
China
Product Name: Ubiquitination-IN-1
Price:
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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