SY-1365

Modify Date: 2025-08-26 07:49:21

SY-1365 Structure
SY-1365 structure
Common Name SY-1365
CAS Number 1816989-16-8 Molecular Weight 587.12
Density N/A Boiling Point N/A
Molecular Formula C31H35ClN8O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SY-1365


SY-1365 is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors[1].

 Names

Name SY-1365

 SY-1365 Biological Activity

Description SY-1365 is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors[1].
Related Catalog
Target

CDK7

References

[1]. Hu S,et al. Discovery and characterization of SY-1365, a selective, covalent inhibitor of CDK7. Cancer Res. 2019 May 7.

 Chemical & Physical Properties

Molecular Formula C31H35ClN8O2
Molecular Weight 587.12
InChIKey SCJNYBYSTCRPAO-LXBQGUBHSA-N
SMILES CN(C)CC=CC(=O)Nc1ccc(C(=O)NC2(C)CCCC(Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)C2)nc1
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