SY-640
Modify Date: 2024-01-13 22:42:59
SY-640 structure
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Common Name | SY-640 | ||
|---|---|---|---|---|
| CAS Number | 168705-70-2 | Molecular Weight | 207.226 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 349.2±21.0 °C at 760 mmHg | |
| Molecular Formula | C11H13NO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 165.0±22.1 °C | |
Use of SY-640SY-640 is an Acetamide derivative and has potent hepatoprotective effect. SY-640 reduces Propionibacterium acnes and Lipopolysaccharide-induced liver injury in mice[1][2]. |
| Name | N-(1,3-Benzodioxol-5-ylmethyl)-N-methylacetamide |
|---|---|
| Synonym | More Synonyms |
| Description | SY-640 is an Acetamide derivative and has potent hepatoprotective effect. SY-640 reduces Propionibacterium acnes and Lipopolysaccharide-induced liver injury in mice[1][2]. |
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| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vitro | SY-640 inhibits the number of liver-infiltrating cells and attenuates the increased expression of leukocyte function-associated antigen-1 on these cells[1]. |
| In Vivo | SY-640 (Oral; 150 mg/kg; once daily for 7 days) significantly inhibits Propionibacterium acnes and Lipopolysaccharide-induced liver injury, but a single administration is without effect[1]. SY-640 (p.o.; 150 mg/kg; once daily for three days) significantly increases the liver microsomal cytochrome P-450 content and aminopyrine demethylase activity in mice. The hepatic microsomal aminopyrine demethylase activity is obviously inhibited two hours after oral administration of SY-640[2]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 349.2±21.0 °C at 760 mmHg |
| Molecular Formula | C11H13NO3 |
| Molecular Weight | 207.226 |
| Flash Point | 165.0±22.1 °C |
| Exact Mass | 207.089539 |
| LogP | 0.89 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.557 |
| Acetamide, N-(1,3-benzodioxol-5-ylmethyl)-N-methyl- |
| N-(1,3-Benzodioxol-5-ylmethyl)-N-methylacetamide |
| MFCD20143110 |