LEM-14

Modify Date: 2025-08-25 09:32:20

LEM-14 Structure
LEM-14 structure
Common Name LEM-14
CAS Number 1814881-70-3 Molecular Weight 478.567
Density N/A Boiling Point N/A
Molecular Formula C25H26N4O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LEM-14


LEM-14 is a specific inhibitor of histone lysine methyltransferase NSD2 (MMSET/WHSC1) with in vitro IC50 of 132 uM, and that is inactive against the closely related NSD1 and NSD3.

 Names

Name LEM-14

 LEM-14 Biological Activity

Description LEM-14 is a specific inhibitor of histone lysine methyltransferase NSD2 (MMSET/WHSC1) with in vitro IC50 of 132 uM, and that is inactive against the closely related NSD1 and NSD3.
References References 1. Shen Y, et al. Biochem Biophys Res Commun. 2018 Nov 21. pii: S0006-291X(18)32443-4. View Related Products by Target Histone Methyltransferase (HMTase)

 Chemical & Physical Properties

Molecular Formula C25H26N4O4S
Molecular Weight 478.567
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