1814881-70-3
1814881-70-3 structure
- Name: LEM-14
- Chemical Name: LEM-14
- CAS Number: 1814881-70-3
- Molecular Formula: C25H26N4O4S
- Molecular Weight: 478.567
- Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
- Create Date: 2020-01-11 18:36:49
- Modify Date: 2025-08-25 09:32:20
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LEM-14 is a specific inhibitor of histone lysine methyltransferase NSD2 (MMSET/WHSC1) with in vitro IC50 of 132 uM, and that is inactive against the closely related NSD1 and NSD3.
| Name | LEM-14 |
|---|
| Description | LEM-14 is a specific inhibitor of histone lysine methyltransferase NSD2 (MMSET/WHSC1) with in vitro IC50 of 132 uM, and that is inactive against the closely related NSD1 and NSD3. |
|---|---|
| References | References 1. Shen Y, et al. Biochem Biophys Res Commun. 2018 Nov 21. pii: S0006-291X(18)32443-4. View Related Products by Target Histone Methyltransferase (HMTase) |
| Molecular Formula | C25H26N4O4S |
|---|---|
| Molecular Weight | 478.567 |