LEM-14
Names
[ CAS No. ]:
1814881-70-3
[ Name ]:
LEM-14
Biological Activity
[Description]:
LEM-14 is a specific inhibitor of histone lysine methyltransferase NSD2 (MMSET/WHSC1) with in vitro IC50 of 132 uM, and that is inactive against the closely related NSD1 and NSD3.
[References]
References 1. Shen Y, et al. Biochem Biophys Res Commun. 2018 Nov 21. pii: S0006-291X(18)32443-4. View Related Products by Target Histone Methyltransferase (HMTase)
Chemical & Physical Properties
[ Molecular Formula ]:
C25H26N4O4S
[ Molecular Weight ]:
478.567
Related Compounds
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