TRC-766
Modify Date: 2025-08-25 20:20:38
TRC-766 structure
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Common Name | TRC-766 | ||
|---|---|---|---|---|
| CAS Number | 1810734-44-1 | Molecular Weight | 524.98 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H24ClF3N2O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TRC-766TRC-766 is a negative control of RTC-5 (TRC-382). TRC-766 binds protein phosphatase 2A (PP2A) and does not activate the phosphatase[1]. |
| Name | TRC-766 |
|---|
| Description | TRC-766 is a negative control of RTC-5 (TRC-382). TRC-766 binds protein phosphatase 2A (PP2A) and does not activate the phosphatase[1]. |
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| Related Catalog | |
| In Vitro | As a pharmacologic control, the cells are treated with increasing doses of TRC-766, which is structurally similar to PP2A (SMAP) but biologically inactive. TRC-766 lacks a key N-H sulfonamide hydrogen bond donor. While TRC-766 still binds PP2A, it does not activate the phosphatase and therefore it was postulated to not affect cell viability[1]. |
| References |
| Molecular Formula | C25H24ClF3N2O3S |
|---|---|
| Molecular Weight | 524.98 |