Remdesivir

Modify Date: 2024-01-03 18:50:24

Remdesivir structure	Common Name	Remdesivir
	CAS Number	1809249-37-3	Molecular Weight	602.576
	Density	1.5±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₅N₆O₈P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Remdesivir

Remdesivir is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for ARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells.

Name	remdesivir
Synonym	More Synonyms

Description	Remdesivir is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for ARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells.
Related Catalog	Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Anti-infection >> SARS-CoV
Target	EC50: 30 nM (murine hepatitis virus, delayed brain tumor cell), 74 nM (SARS-CoV, HAE cell), 74 nM (MERS-CoV, HAE cell)[1]
In Vitro	Remdesivir (GS-5734) is a potent antiviral agent. Remdesivir inhibits murine hepatitis virus (MHV) with an EC50 of 30 nM, and blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 nM in HAE cells after treatment for 24 h[1].
References	[1]. Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18. [2]. Wang M, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 Mar;30(3):269-271.

Density	1.5±0.1 g/cm3
Molecular Formula	C₂₇H₃₅N₆O₈P
Molecular Weight	602.576
Exact Mass	602.225403
LogP	2.10
Index of Refraction	1.652
Storage condition	2-8℃

UNII:3QKI37EEHE

GS-5734

remdesivir

GL Biochem (Shanghai) Ltd.
China
Product Name: Remdesivir
Price: ￥Inquiry/1kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Remdesivir
Price: ￥150000.0/1kg ￥300.0/100mg ￥800.0/1g
Purity: 95.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Remdesivir(GS-5734)
Price: $600.0/100mg $1800.0/1g $1000.0/250mg ￥4700.0/5g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 1809249-37-3
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Price: ￥7291/10 mM * 1 mL in DMSO

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