Benzyl-PEG5-Ms

Modify Date: 2024-01-10 12:35:49

Benzyl-PEG5-Ms Structure
Benzyl-PEG5-Ms structure
Common Name Benzyl-PEG5-Ms
CAS Number 1807539-07-6 Molecular Weight 406.491
Density 1.2±0.1 g/cm3 Boiling Point 529.4±50.0 °C at 760 mmHg
Molecular Formula C18H30O8S Melting Point N/A
MSDS N/A Flash Point 274.0±30.1 °C

 Use of Benzyl-PEG5-Ms


Benzyl-PEG5-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-Phenyl-2,5,8,11,14-pentaoxahexadecan-16-yl methanesulfonate
Synonym More Synonyms

 Benzyl-PEG5-Ms Biological Activity

Description Benzyl-PEG5-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 529.4±50.0 °C at 760 mmHg
Molecular Formula C18H30O8S
Molecular Weight 406.491
Flash Point 274.0±30.1 °C
Exact Mass 406.166138
LogP 0.06
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.498

 Synonyms

MFCD28976666
1-Phenyl-2,5,8,11,14-pentaoxahexadecan-16-yl methanesulfonate
2,5,8,11,14-Pentaoxahexadecan-16-ol, 1-phenyl-, methanesulfonate
Benzyl-PEG5-MS
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