BP-5-087

Modify Date: 2023-01-13 14:16:23

BP-5-087 structure	Common Name	BP-5-087
	CAS Number	1803281-30-2	Molecular Weight	770.691
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₆H₃₀F₈N₂O₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BP-5-087

A potent, selective STAT3 SH2 domain inhibitor (EC50=5.6 uM) that reduces STAT3 phosphorylation and nuclear transactivation; restores TKI sensitivity to therapy-resistant CML progenitor cells in primary cells from CML patients with BCR-ABL1 kinase-independent TKI resistance, including leukemic stem cells.

Name	BP-5-087

Description	A potent, selective STAT3 SH2 domain inhibitor (EC50=5.6 uM) that reduces STAT3 phosphorylation and nuclear transactivation; restores TKI sensitivity to therapy-resistant CML progenitor cells in primary cells from CML patients with BCR-ABL1 kinase-independent TKI resistance, including leukemic stem cells.
References	References 1. Eiring AM, et al. Leukemia. 2015 Mar;29(3):586-597. 2. Eiring AM, et al. Leuk Suppl. 2014 Dec;3(Suppl 1):S5-6. View Related Products by Target STAT

Molecular Formula	C₃₆H₃₀F₈N₂O₆S
Molecular Weight	770.691

DC Chemicals Limited
China
Product Name: BP-5-087
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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