DMEA-PNU-159682 dichloroacetate

Modify Date: 2024-01-12 17:54:18

DMEA-PNU-159682 dichloroacetate structure	Common Name	DMEA-PNU-159682 dichloroacetate
	CAS Number	1799421-49-0	Molecular Weight	1013.65
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₁H₄₉Cl₄N₃O₁₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DMEA-PNU-159682 dichloroacetate

DMEA-PNU-159682 (molecule D12) dichloroacetate is an ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682[1][2].

Name	DMEA-PNU-159682 dichloroacetate

Description	DMEA-PNU-159682 (molecule D12) dichloroacetate is an ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin
References	[1]. Chen Jingkang, et al. Disubstituted maleic amide class connexon for antibody-drug conjugate and its preparation method and application. CN108101825A. [2]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1

Description

DMEA-PNU-159682 (molecule D12) dichloroacetate is an ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682[1][2].

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin

References

[1]. Chen Jingkang, et al. Disubstituted maleic amide class connexon for antibody-drug conjugate and its preparation method and application. CN108101825A.

[2]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1

Molecular Formula	C₄₁H₄₉Cl₄N₃O₁₈
Molecular Weight	1013.65

DMEA-PNU-159682 dichloroacetate

Use of DMEA-PNU-159682 dichloroacetate

Names

DMEA-PNU-159682 dichloroacetate Biological Activity

Chemical & Physical Properties