2259318-54-0

2259318-54-0 structure

Name: Mal-Phe-C4-VC-PAB-DMEA-PNU-159682
Chemical Name: Mal-Phe-C4-VC-PAB-DMEA-PNU-159682
CAS Number: 2259318-54-0
Molecular Formula: C₇₀H₈₃N₉O₂₂
Molecular Weight: 1402.46
Catalog: Research Areas Cancer
Create Date: 2019-12-08 17:56:19
Modify Date: 2024-01-09 11:38:46
Mal-Phe-C4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker Mal-Phe-C4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1].

Name	Mal-Phe-C4-VC-PAB-DMEA-PNU-159682

Description	Mal-Phe-C4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker Mal-Phe-C4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1].
Related Catalog	Research Areas >> Cancer
References	[1]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1

Molecular Formula	C₇₀H₈₃N₉O₂₂
Molecular Weight	1402.46