1799421-49-0

1799421-49-0 structure

Name: DMEA-PNU-159682 dichloroacetate
Chemical Name: DMEA-PNU-159682 dichloroacetate
CAS Number: 1799421-49-0
Molecular Formula: C₄₁H₄₉Cl₄N₃O₁₈
Molecular Weight: 1013.65
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Cytotoxin
Create Date: 2023-04-26 10:48:01
Modify Date: 2024-01-12 17:54:18
DMEA-PNU-159682 (molecule D12) dichloroacetate is an ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682[1][2].

Name	DMEA-PNU-159682 dichloroacetate

Description	DMEA-PNU-159682 (molecule D12) dichloroacetate is an ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin
References	[1]. Chen Jingkang, et al. Disubstituted maleic amide class connexon for antibody-drug conjugate and its preparation method and application. CN108101825A. [2]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1

Molecular Formula	C₄₁H₄₉Cl₄N₃O₁₈
Molecular Weight	1013.65