AR 420626

Modify Date: 2024-01-12 07:19:04

AR 420626 Structure
AR 420626 structure
Common Name AR 420626
CAS Number 1798310-55-0 Molecular Weight 417.285
Density 1.4±0.1 g/cm3 Boiling Point 619.3±55.0 °C at 760 mmHg
Molecular Formula C21H18Cl2N2O3 Melting Point N/A
MSDS N/A Flash Point 328.3±31.5 °C

 Use of AR 420626


AR420626 is a selective agonist of free fatty acid receptor 3 (FFAR3, GPR41) with IC50 of 117 nM. AR420626 inhibits nicotine and serotonin-induced changes in motility of isolated muscle strips from rat colon and suppresses serotonin-induced fecal output in rats[1].

 Names

Name AR420626
Synonym More Synonyms

 AR 420626 Biological Activity

Description AR420626 is a selective agonist of free fatty acid receptor 3 (FFAR3, GPR41) with IC50 of 117 nM. AR420626 inhibits nicotine and serotonin-induced changes in motility of isolated muscle strips from rat colon and suppresses serotonin-induced fecal output in rats[1].
Related Catalog
References

[1]. Kaji I, et al. Free fatty acid receptor 3 activation suppresses neurogenic motility in rat proximal colon. Neurogastroenterol Motil. 2018 Jan;30(1):10.1111/nmo.13157.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 619.3±55.0 °C at 760 mmHg
Molecular Formula C21H18Cl2N2O3
Molecular Weight 417.285
Flash Point 328.3±31.5 °C
Exact Mass 416.069458
LogP 3.71
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.653

 Synonyms

3-Quinolinecarboxamide, N-(2,5-dichlorophenyl)-4-(2-furanyl)-1,4,5,6,7,8-hexahydro-2-methyl-5-oxo-
AR420626
N-(2,5-Dichlorophenyl)-4-(2-furyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxamide
N-(2,5-Dichlorophenyl)-4-(furan-2-yl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydro-quinoline-3-carboxamide
AR 420626
MFCD28987470