DiaPep277
Modify Date: 2024-04-03 11:39:18
DiaPep277 structure
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Common Name | DiaPep277 | ||
|---|---|---|---|---|
| CAS Number | 179822-83-4 | Molecular Weight | 2390.73 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C106H180N28O34 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DiaPep277DiaPep277 is a 24 amino acid peptide derived from positions 437-460 in HSP60. DiaPep277 arrests the progression of β-cell destruction in NOD mice. DiaPep277 has an immune modulatory effect on diabetogenic T cells in animal models of diabetes[1][2]. |
| Name | DiaPep277 |
|---|
| Description | DiaPep277 is a 24 amino acid peptide derived from positions 437-460 in HSP60. DiaPep277 arrests the progression of β-cell destruction in NOD mice. DiaPep277 has an immune modulatory effect on diabetogenic T cells in animal models of diabetes[1][2]. |
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| Related Catalog | |
| In Vivo | DiaPep277 (50 μg; i.p.; single dosage) causes strong splenic T cells responses, and strong diabetogenic clones 27, C7, and C9 responses[2]. Animal Model: Female NOD mice (diabetes model)[2] Dosage: 50 μg Administration: i.p.; single dosage Result: Caused strong splenic T cells responses, and strong diabetogenic clones 27, C7, and C9 responses. |
| Molecular Formula | C106H180N28O34 |
|---|---|
| Molecular Weight | 2390.73 |
| InChIKey | VGGRNGOEDNBLPH-YJHCMWSWSA-N |
| SMILES | CCC(C)C(NC(=O)C(NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(NC(=O)CNC(=O)CNC(=O)CNC(=O)C(CC(C)C)NC(=O)C(N)C(C)C)C(C)C)C(C)C)C(=O)N1CCCC1C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(C(=O)N1CCCC1C(=O)NC(C)C(=O)NC(CC(N)=O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)O)C(C)O |