179822-83-4
179822-83-4 structure
- Name: DiaPep277
- Chemical Name: DiaPep277
- CAS Number: 179822-83-4
- Molecular Formula: C106H180N28O34
- Molecular Weight: 2390.73
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2023-05-19 01:13:58
- Modify Date: 2024-04-03 11:39:18
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DiaPep277 is a 24 amino acid peptide derived from positions 437-460 in HSP60. DiaPep277 arrests the progression of β-cell destruction in NOD mice. DiaPep277 has an immune modulatory effect on diabetogenic T cells in animal models of diabetes[1][2].
| Name | DiaPep277 |
|---|
| Description | DiaPep277 is a 24 amino acid peptide derived from positions 437-460 in HSP60. DiaPep277 arrests the progression of β-cell destruction in NOD mice. DiaPep277 has an immune modulatory effect on diabetogenic T cells in animal models of diabetes[1][2]. |
|---|---|
| Related Catalog | |
| In Vivo | DiaPep277 (50 μg; i.p.; single dosage) causes strong splenic T cells responses, and strong diabetogenic clones 27, C7, and C9 responses[2]. Animal Model: Female NOD mice (diabetes model)[2] Dosage: 50 μg Administration: i.p.; single dosage Result: Caused strong splenic T cells responses, and strong diabetogenic clones 27, C7, and C9 responses. |
| Molecular Formula | C106H180N28O34 |
|---|---|
| Molecular Weight | 2390.73 |