DDR2-IN-5
Modify Date: 2025-09-18 12:42:30
DDR2-IN-5 structure
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Common Name | DDR2-IN-5 | ||
|---|---|---|---|---|
| CAS Number | 1796592-06-7 | Molecular Weight | 605.666 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H34F3N7O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DDR2-IN-5DDR2-IN-5 is a potent, dual DDR2/SRC inhibitor with IC50 of 56/12 nM, potently suppresses DDR2 mutated cell lines HCC-366 and NCI-H2286 with IC50 of 0.44 uM and 0.29 uM. |
| Name | DDR2-IN-5 |
|---|
| Description | DDR2-IN-5 is a potent, dual DDR2/SRC inhibitor with IC50 of 56/12 nM, potently suppresses DDR2 mutated cell lines HCC-366 and NCI-H2286 with IC50 of 0.44 uM and 0.29 uM. |
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| References | References 1. Terai H, et al. ACS Chem Biol. 2015 Dec 18;10(12):2687-96. View Related Products by Target Discoidin Domain Receptor (DDR) |
| Molecular Formula | C32H34F3N7O2 |
|---|---|
| Molecular Weight | 605.666 |
| InChIKey | GZOONDJISKPFEJ-UHFFFAOYSA-N |
| SMILES | CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(NC(=O)c4cncc(-c5cnn(C)c5)c4)c3)cc2C(F)(F)F)CC1 |