DDR2-IN-5

Names

[ Name ]:
DDR2-IN-5

Biological Activity

[Description]:

DDR2-IN-5 is a potent, dual DDR2/SRC inhibitor with IC50 of 56/12 nM, potently suppresses DDR2 mutated cell lines HCC-366 and NCI-H2286 with IC50 of 0.44 uM and 0.29 uM.

[References]

References 1. Terai H, et al. ACS Chem Biol. 2015 Dec 18;10(12):2687-96. View Related Products by Target Discoidin Domain Receptor (DDR)

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₃₄F₃N₇O₂

[ Molecular Weight ]:
605.666

Related Compounds

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