GW284543 hydrochloride

Modify Date: 2025-08-25 20:48:48

GW284543 hydrochloride structure	Common Name	GW284543 hydrochloride
	CAS Number	179246-08-3	Molecular Weight	408.88
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₁ClN₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GW284543 hydrochloride

GW284543 (UNC10225170) hydrochloride is a selective MEK5 inhibitor. GW284543 reduces pERK5, and decreases endogenous MYC protein[1].

Name	GW 284543 hydrochloride-UNC 10225170 hydrochloride

Description	GW284543 (UNC10225170) hydrochloride is a selective MEK5 inhibitor. GW284543 reduces pERK5, and decreases endogenous MYC protein[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> MEK
Target	MEK5
In Vitro	GW284543 (10 and 20 μM; 6 h) treatment inhibits MEK5 in a dose-dependent manner and reduces pERK5[1]. Western Blot Analysis[1] Cell Line: MIA PaCa-2 cells Concentration: 10 and 20 μM Incubation Time: 6 hours Result: Reduced phosphorylation of ERK5, and decreased endogenous MYC protein.
References	[1]. Vaseva AV, et al. KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism. Cancer Cell. 2018 Nov 12;34(5):807-822.e7.

Molecular Formula	C₂₃H₂₁ClN₂O₃
Molecular Weight	408.88
Storage condition	Sealed in dry,Room Temperature

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: GW284543 hydrochloride
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

GW284543 hydrochloride suppliers

GW284543 hydrochloride price