R 568 hydrochloride

Modify Date: 2025-08-26 00:11:51

R 568 hydrochloride structure	Common Name	R 568 hydrochloride
	CAS Number	177172-49-5	Molecular Weight	340.28700
	Density	N/A	Boiling Point	416.3ºC at 760 mmHg
	Molecular Formula	C₁₈H₂₃Cl₂NO	Melting Point	N/A
	MSDS	N/A	Flash Point	205.6ºC

Use of R 568 hydrochloride

Tecalcet Hydrochloride (R 568 Hydrochloride), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet Hydrochloride (R 568 Hydrochloride) increases the sensitivity to activation by extracellular Ca2+[1][2][3].

Name	3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine,hydrochloride
Synonym	More Synonyms

Description	Tecalcet Hydrochloride (R 568 Hydrochloride), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet Hydrochloride (R 568 Hydrochloride) increases the sensitivity to activation by extracellular Ca2+[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> CaSR
References	[1]. Wada, M., et al. The calcimimetic compound NPS R-568 suppresses parathyroid cell proliferation in rats with renal insufficiency. Control of parathyroid cell growth via a calcium receptor. Journal of Clinical Investigation 100(12), 2977-2983 (1997). [2]. Nemeth, E.F., et al. The parathyroid calcium receptor: a novel therapeutic target for treating hyperparathyroidism. Pediatr.Nephrol. 10(3), 275-279 (1996). [3]. Nemeth, E.F., et al. Calcimimetics with potent and selective activity on the parathyroid calcium receptor. Proceedings of the National Academy of Sciences of the United States of America 95(7), 4040-4045 (1998).

Description

Related Catalog

Research Areas >> Others

Signaling Pathways >> GPCR/G Protein >> CaSR

References

[1]. Wada, M., et al. The calcimimetic compound NPS R-568 suppresses parathyroid cell proliferation in rats with renal insufficiency. Control of parathyroid cell growth via a calcium receptor. Journal of Clinical Investigation 100(12), 2977-2983 (1997).

[2]. Nemeth, E.F., et al. The parathyroid calcium receptor: a novel therapeutic target for treating hyperparathyroidism. Pediatr.Nephrol. 10(3), 275-279 (1996).

[3]. Nemeth, E.F., et al. Calcimimetics with potent and selective activity on the parathyroid calcium receptor. Proceedings of the National Academy of Sciences of the United States of America 95(7), 4040-4045 (1998).

Boiling Point	416.3ºC at 760 mmHg
Molecular Formula	C₁₈H₂₃Cl₂NO
Molecular Weight	340.28700
Flash Point	205.6ºC
Exact Mass	339.11600
PSA	21.26000
LogP	5.82490
Vapour Pressure	3.86E-07mmHg at 25°C

Norcalcin

R-568

Tecalcet hydrochloride

KRN-568

NPS R-568

Tecalcet HCl

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: R 568 hydrochloride
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Tecalcet hydrochloride
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: Tecalcet hydrochloride
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.