L-670,596
Modify Date: 2024-04-02 17:42:20
L-670,596 structure
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Common Name | L-670,596 | ||
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| CAS Number | 121083-05-4 | Molecular Weight | 433.47 | |
| Density | 1.43g/cm3 | Boiling Point | 693.4ºC at 760mmHg | |
| Molecular Formula | C22H21F2NO4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 373.2ºC | |
Use of L-670,596L-670596 is an orally active and selective thrombsxane A2 receptor/prostaglandin receptor antagonist. L-670596 inhibits arachidonic acid (HY-109590) and U-44069 induced bronchoconstriction in the guinea pig. L-670596 also inhibits the aggregation of human platelet rich plasma induced by U-44069[1][2]. |
| Name | 2-[6,8-difluoro-9-[(4-methylsulfonylphenyl)methyl]-1,2,3,4-tetrahydrocarbazol-1-yl]acetic acid |
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| Synonym | More Synonyms |
| Description | L-670596 is an orally active and selective thrombsxane A2 receptor/prostaglandin receptor antagonist. L-670596 inhibits arachidonic acid (HY-109590) and U-44069 induced bronchoconstriction in the guinea pig. L-670596 also inhibits the aggregation of human platelet rich plasma induced by U-44069[1][2]. |
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| Related Catalog | |
| In Vitro | L-670596 抑制 U-44069 诱导的人类富血小板血浆的聚集[1]。 |
| In Vivo | L-670596 (0.03 mg/kg ; i.v.; single) 抑制豚鼠中花生四烯酸和 U-44069 诱导的支气管收缩[1]。 L-670596 (2 mg/kg; i.v.; single) 抑制猪的血小板聚集成胶原蛋白[2]。 Animal Model: Guinea pig (arachidonic acid and U-44069 induced bronchoconstriction model)[1]. Dosage: 0.03mg/kg Administration: Intravenous injection; single. Result: Inhibited arachidonic acid and U-44069 induced bronchoconstriction. |
| References |
| Density | 1.43g/cm3 |
|---|---|
| Boiling Point | 693.4ºC at 760mmHg |
| Molecular Formula | C22H21F2NO4S |
| Molecular Weight | 433.47 |
| Flash Point | 373.2ºC |
| Exact Mass | 433.11600 |
| PSA | 84.75000 |
| LogP | 5.34670 |
| Vapour Pressure | 3.46E-20mmHg at 25°C |
| Index of Refraction | 1.636 |
| R 568 hydrochloride |
| HMS3268M18 |
| L-670,596 |