S-17092

Modify Date: 2024-09-16 17:59:31

S-17092 Structure
S-17092 structure
 Common Name S-17092
CAS Number 176797-26-5 Molecular Weight 384.53500
Density N/A Boiling Point N/A
Molecular Formula C22H28N2O2S Melting Point N/A
MSDS USA Flash Point N/A
Symbol GHS07
GHS07		 Signal Word Warning

 Use of S-17092


S 17092 (S 17092-1) is a potent cerebral prolyl-endopeptidase (PEP) inhibitor with an IC50 of 1.2 nM. S 17092 can be used for the research of memory impairment and cognitive disorders associated with cerebral aging[1].

 Names

Name [(2S,3aS,7aS)-2-(1,3-thiazolidine-3-carbonyl)-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-[(1R,2R)-2-phenylcyclopropyl]methanone
Synonym More Synonyms

 S-17092 Biological Activity

Description S 17092 (S 17092-1) is a potent cerebral prolyl-endopeptidase (PEP) inhibitor with an IC50 of 1.2 nM. S 17092 can be used for the research of memory impairment and cognitive disorders associated with cerebral aging[1].
Related Catalog
References

[1]. Philippe Morain, et al. S 17092: a prolyl endopeptidase inhibitor as a potential therapeutic drug for memory impairment. Preclinical and clinical studies. CNS Drug Rev. Spring 2002;8(1):31-52.

 Chemical & Physical Properties

Molecular Formula C22H28N2O2S
Molecular Weight 384.53500
Exact Mass 384.18700
PSA 65.92000
LogP 3.35850

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
RIDADR NONH for all modes of transport

 Articles1

More Articles
Hypothalamic prolyl endopeptidase (PREP) regulates pancreatic insulin and glucagon secretion in mice. Kim JD, Toda C, D'Agostino G, et al.

Proc. Natl. Acad. Sci. U. S. A. 111(32) , 11876-81, (2014)

 Synonyms

S-17092
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Chemsrc provides S-17092(CAS#:176797-26-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of S-17092 are included as well.>> amp version: S-17092

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