3,5-bis-(4-Nitrophenoxy)benzoic acid

Modify Date: 2025-09-16 09:27:40

3,5-bis-(4-Nitrophenoxy)benzoic acid structure	Common Name	3,5-bis-(4-Nitrophenoxy)benzoic acid
	CAS Number	173550-33-9	Molecular Weight	396.30700
	Density	1.485g/cm3	Boiling Point	577.655ºC at 760 mmHg
	Molecular Formula	C₁₉H₁₂N₂O₈	Melting Point	232 °C
	MSDS	N/A	Flash Point	303.155ºC

Use of 3,5-bis-(4-Nitrophenoxy)benzoic acid

3,5-Bis(4-nitrophenoxy)benzoic acid is an inhibitor of γ-secretase. 3,5-Bis(4-nitrophenoxy)benzoic acid causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25). 3,5-Bis(4-nitrophenoxy)benzoic acid, as a marker for fetal hypothyroidism, is a 3,3’-diiodothyronine sulfate (T2S) cross-reactive material in maternal serum[1].

Name	3,5-Bis(4-nitrophenoxy)benzoic Acid
Synonym	More Synonyms

Description	3,5-Bis(4-nitrophenoxy)benzoic acid is an inhibitor of γ-secretase. 3,5-Bis(4-nitrophenoxy)benzoic acid causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25). 3,5-Bis(4-nitrophenoxy)benzoic acid, as a marker for fetal hypothyroidism, is a 3,3’-diiodothyronine sulfate (T2S) cross-reactive material in maternal serum[1].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Wu SY, et al. Compound W, a 3,3'-diiodothyronine sulfate cross-reactive substance in serum from pregnant women--a potential marker for fetal thyroid function. Pediatr Res. 2007;61(3):307-312. [2]. Ran Y, et al. Differential Inhibition of Signal Peptide Peptidase Family Members by Established γ-Secretase Inhibitors. PLoS One. 2015;10(6):e0128619. Published 2015 Jun 5. [3]. Greife A, et al. Canonical Notch signalling is inactive in urothelial carcinoma. BMC Cancer. 2014;14:628. Published 2014 Aug 29.

Description

Related Catalog

Research Areas >> Metabolic Disease

References

[1]. Wu SY, et al. Compound W, a 3,3'-diiodothyronine sulfate cross-reactive substance in serum from pregnant women--a potential marker for fetal thyroid function. Pediatr Res. 2007;61(3):307-312.

[2]. Ran Y, et al. Differential Inhibition of Signal Peptide Peptidase Family Members by Established γ-Secretase Inhibitors. PLoS One. 2015;10(6):e0128619. Published 2015 Jun 5.

[3]. Greife A, et al. Canonical Notch signalling is inactive in urothelial carcinoma. BMC Cancer. 2014;14:628. Published 2014 Aug 29.

Density	1.485g/cm3
Boiling Point	577.655ºC at 760 mmHg
Melting Point	232 °C
Molecular Formula	C₁₉H₁₂N₂O₈
Molecular Weight	396.30700
Flash Point	303.155ºC
Exact Mass	396.05900
PSA	147.40000
LogP	5.83220
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.666
InChIKey	JOSXKPZXMVHRKU-UHFFFAOYSA-N
SMILES	O=C(O)c1cc(Oc2ccc([N+](=O)[O-])cc2)cc(Oc2ccc([N+](=O)[O-])cc2)c1

3,5-bis-(4-Nitrophenoxy)benzoic acid MSDS(Chinese)

HS Code	2918990090

Precursor 3
CAS#:173550-32-8 methyl 3,5-bis(... CAS#:99-10-5 3,5-Dihydroxybe... CAS#:350-46-9 1-Fluoro-4-nitr...
DownStream 1
CAS#:195189-45-8 3,5-bis-(4-Amin...

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

MFCD02093450

3,5-BIS(4-NITROPHENOXY)BENZOIC ACID

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 3,5-bis-(4-Nitrophenoxy)benzoic acid
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Compound W
Price: ￥Inquiry/250mg ￥Inquiry/100mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3,5-bis-(4-Nitrophenoxy)benzoic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.